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Miki Nakajima Selected Research

Flutamide (Eulexin)

10/2012Involvement of Th2 cytokines in the mouse model of flutamide-induced acute liver injury.
6/2012Contributions of arylacetamide deacetylase and carboxylesterase 2 to flutamide hydrolysis in human liver.
7/2009Human arylacetamide deacetylase is a principal enzyme in flutamide hydrolysis.

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Miki Nakajima Research Topics

Disease

21Neoplasms (Cancer)
04/2023 - 11/2002
15Chemical and Drug Induced Liver Injury
12/2017 - 10/2009
12Hepatocellular Carcinoma (Hepatoma)
01/2022 - 02/2002
10Breast Neoplasms (Breast Cancer)
08/2019 - 06/2002
6Inflammation (Inflammations)
01/2022 - 02/2011
5Liver Diseases (Liver Disease)
12/2017 - 12/2005
5Carcinogenesis
05/2013 - 05/2004
5Infections
05/2011 - 08/2007
4Prostatic Neoplasms (Prostate Cancer)
11/2021 - 07/2009
4Wounds and Injuries (Trauma)
01/2020 - 10/2012
4Adenocarcinoma
07/2006 - 06/2002
3Mental Disorders (Mental Disorder)
01/2024 - 07/2006
3Hepatitis
01/2014 - 12/2005
3Lung Neoplasms (Lung Cancer)
04/2010 - 08/2005
3Carcinoma (Carcinomatosis)
05/2003 - 06/2002
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2023 - 09/2021
2Idiopathic Pulmonary Fibrosis
01/2023 - 12/2021
2Parkinson Disease (Parkinson's Disease)
01/2021 - 08/2005
2Anaphylaxis (Anaphylactic Shock)
01/2021 - 12/2014
2Type 2 Diabetes Mellitus (MODY)
01/2019 - 10/2018
2Neoplasm Metastasis (Metastasis)
12/2017 - 10/2015
2Non-alcoholic Fatty Liver Disease
12/2017 - 01/2012
2Necrosis
07/2015 - 08/2014
2Leukemia
07/2014 - 01/2012
2Cardiovascular Diseases (Cardiovascular Disease)
10/2013 - 09/2011
2Methemoglobinemia
06/2013 - 11/2012
2Renal Insufficiency (Renal Failure)
11/2012 - 09/2010
2Cholestasis
10/2012 - 01/2012
2Fatty Liver
01/2012 - 01/2002
2Tobacco Use Disorder (Nicotine Dependence)
12/2007 - 09/2006
2Leukopenia
06/2007 - 06/2005
2Endometrial Neoplasms (Endometrial Cancer)
07/2006 - 04/2006
2Embryonal Carcinoma
04/2003 - 06/2002
2Renal Cell Carcinoma (Grawitz Tumor)
04/2003 - 06/2002
1COVID-19
03/2024
1Hyperglycemia
01/2023
1Dyslipidemias (Dyslipidemia)
01/2023
1Osteoporosis
04/2022
1Chronic Renal Insufficiency
04/2022
1Adrenal Insufficiency (Adrenal Gland Hypofunction)
01/2022
1Cataract (Cataracts)
01/2022
1Sarcoma (Soft Tissue Sarcoma)
09/2021
1Colorectal Neoplasms (Colorectal Cancer)
09/2021

Drug/Important Bio-Agent (IBA)

15Proteins (Proteins, Gene)FDA Link
01/2022 - 02/2005
12Messenger RNA (mRNA)IBA
01/2022 - 04/2003
11MicroRNAs (MicroRNA)IBA
09/2021 - 10/2009
9Biomarkers (Surrogate Marker)IBA
09/2021 - 09/2011
8EnzymesIBA
03/2024 - 02/2005
5Cytochrome P-450 CYP3AIBA
10/2015 - 06/2005
5NicotineFDA Link
12/2007 - 11/2002
4Estrogens (Estrogen)FDA Link
12/2017 - 05/2004
4Small Interfering RNA (siRNA)IBA
04/2010 - 08/2007
3Alanine Transaminase (SGPT)IBA
01/2022 - 08/2007
3XenobioticsIBA
01/2013 - 09/2011
3Flutamide (Eulexin)FDA LinkGeneric
10/2012 - 07/2009
3Troglitazone (Rezulin)FDA Link
12/2005 - 02/2002
2ProdrugsIBA
03/2024 - 11/2021
2tipepidineIBA
01/2024 - 04/2023
2CytokinesIBA
04/2023 - 02/2015
2Rifampin (Rifampicin)FDA LinkGeneric
01/2023 - 12/2011
2GlucuronidesIBA
01/2023 - 12/2014
2immune RNA (I-RNA)IBA
10/2020 - 01/2017
2RNA (Ribonucleic Acid)IBA
01/2020 - 01/2012
2VildagliptinIBA
01/2019 - 10/2018
2Estrogen ReceptorsIBA
12/2017 - 10/2012
2Carbamazepine (Tegretol)FDA LinkGeneric
01/2016 - 11/2012
2Anticonvulsants (Antiepileptic Drugs)IBA
01/2016 - 11/2013
2Acetaminophen (Paracetamol)FDA LinkGeneric
08/2014 - 10/2012
2Phenytoin (Dilantin)FDA LinkGeneric
11/2013 - 09/2007
2Cytochrome P-450 CYP1A2 (CYP1A2)IBA
11/2012 - 09/2003
2Analgesics (Analgesic Drugs)IBA
11/2012 - 04/2007
2PhenacetinIBA
11/2012 - 09/2010
2Diclofenac (SR 38)FDA LinkGeneric
10/2012 - 05/2011
2TamoxifenFDA LinkGeneric
10/2012 - 01/2012
2Androgen Antagonists (Antiandrogens)IBA
06/2012 - 07/2009
2Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
05/2012 - 04/2003
2LuciferasesIBA
05/2004 - 05/2003
1remdesivirIBA
03/2024
1molnupiravirIBA
03/2024
1Antitussive Agents (Antitussives)FDA Link
01/2024
1Cytochrome P-450 CYP2D6 InhibitorsIBA
04/2023
1Simvastatin (Zocor)FDA LinkGeneric
01/2023
1nintedanibIBA
01/2023
1efavirenz (Sustiva)FDA Link
01/2023
1Nucleotide AptamersIBA
04/2022
1VitaminsIBA
04/2022
1Cytochrome P450 Family 24IBA
04/2022
1Vitamin D3 24-HydroxylaseIBA
04/2022
1pirinixic acidIBA
01/2022
1fenofibric acidFDA Link
01/2022
1Ketoconazole (Nizoral)FDA LinkGeneric
01/2022
1LigandsIBA
01/2022
1CorticosteroneIBA
01/2022
1CholesterolIBA
01/2022
1pirfenidoneIBA
12/2021
1Abiraterone AcetateIBA
11/2021
1abirateroneIBA
11/2021

Therapy/Procedure

13Drug Therapy (Chemotherapy)
01/2018 - 02/2005
5Therapeutics
01/2020 - 08/2005
1Castration
11/2021